Uv radiation damages the dna of cells, typically thymine dimerization, which when unrepaired can create mutations in the genes of the cell. When the cell divides, these mutations are propagated to new generations of cells. If mutations occur in the proto-oncogenes or tumor suppressor genes, the rate of mitosis of the cells carrying the mutation can become uncontrolled, leading to the formation of a tumor.
Occasional extreme sun exposure is causally related to melanoma. Melanoma is most common in men in the back and legs in women. The risk appears to be strongly influenced by the socioeconomic conditions rather than outdoor occupations facing the inside, but is most common in professional and managerial workers unskilled.
Other factors are mutations or complete loss of tumor suppressor genes. The use of sunbeds has been associated with the development of skin cancer, including melanoma. Possible important elements in determining risk include the intensity and duration of sun exposure, the age at which sun exposure occurs, and the degree of skin pigmentation.
Exposure during childhood is an important risk factor than exposure in adulthood. Individuals with blistering or peeling sunburns (especially in the first twenty years of life) have a significantly higher risk of developing melanoma. This does not mean that sunburn is the cause of melanoma. Instead, it is only statistically correlated. The cause is excessive uv exposure.
The red-headed and fair, people with multiple atypical nevi or dysplastic nevi and persons born with giant congenital melanocytic nevi are at increased risk. A family history of melanoma increases the risk of a person because of mutations in cdkn2a, cdk4 and other genes have been found in areas prone to melanoma families. Patients with a history of melanoma are at increased risk of developing a second primary tumor.
The incidence of melanoma has increased in recent years, but it is unclear to what extent changes in behavior in the environment, or early detection are involved. To understand how sunscreen can reduce sunburn and melanoma, while the same cause, it is necessary to distinguish between direct dna damage and indirect dna damage.
Genetic analysis has shown that 92% of melanomas are caused by indirect dna damage. Although some people believe that dark skinned people as the descendants of africans can not get sunburn, are in fact susceptible, and therefore can sunscreen as sunscreen has been shown to protect against other cancers such as carcinoma squamous cell and basal cell carcinoma.
Nevicurative is a powerful natural treatment all topics proven to eliminate and defeat the moles or nevi. Nevicurative pharmacological force provides effective removal of moles without scarring, tissue damage, or recurrence. The treatment is painless and offers profound results in the removal of moles, returning skin tissue to its original state.
Recent clinical trials have established the ability of the active components in nevicurative to effectively eradicate skin moles and affect the growth of human melanoma cells. Nevicurative therefore has shown that even remove most stubborn spots, regardless of their location in the body, even when other treatments have failed.
Nevicurative is well known for its antioxidant properties. It is composed of certified organic extracts of medicinal plants, which have demonstrated their ability to eradicate melanomas and skin tumors in laboratory tests. These extracts have a remarkable range of biochemical and pharmacological properties, which are very effective in eradicating moles.
Scientific results underscore the fact that nevicurative, through its multiple effects on malignant cells, it is useful against melanomas and moles. Because of its effectiveness in removing moles, nevicurative has established a reputation as a mass treatment can not be beaten.